Hamaoui E, Hamaoui M. Nutritional assessment and support during pregnancy. Gastroenterol Clin North Am ; Ladipo O. Nutrition in pregnancy: mineral and vitamin supplements.
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Objective: To describe the physiological pattern of gestational plasma volume adjustments in normal singleton pregnancy and compare this with the pattern in pregnancies complicated by pregnancy-induced hypertension, pre-eclampsia or fetal growth restriction. Methods: We performed a meta-analysis of the current literature on plasma volume adjustments during physiological and complicated pregnancies.
Included studies reported both reference plasma volume measurements non-pregnant, prepregnancy or postpartum and measurements obtained during predetermined gestational ages. Mean differences bet ween the reference and pregnancy plasma volume measurements were calculated for predefined intervals of gestational age using a random-effects model described by DerSimonian and Laird.
Results: Thirty studies were included in the meta-analysis with publication dates ranging from to Plasma volume increased in the first weeks of pregnancy, with the steepest increase occurring during the second trimester. Plasma volume continued to increase in the third trimester with a pooled maximum increase of 1. The plasma volume expansion in gestational hypertensive and growth-restricted pregnancies was 0.
Conclusions: During physiological pregnancy, plasma volume increases by, on average, more than 1 L as compared with non-pregnant conditions. In pregnancies complicated by pregnancy-induced hypertension, pre-eclampsia or fetal growth restriction, plasma volume increase in the third trimester is Keywords: blood volume; complicated pregnancy; physiology; plasma volume; pre-eclampsia; pregnancy.
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Plasma Volume Actions. Pregnancy Actions. Pregnancy Trimester, Third Actions. Full-text links [x] Wiley. Copy Download.
2008, Número 1
Ginecología y obstetricia esencial