Objective: To estimate the procedure-related risk of miscarriage after amniocentesis and chorionic villus sampling CVS based on a systematic review of the literature and an updated meta-analysis. Eligible for inclusion were large controlled studies reporting data for pregnancy loss prior to 24 weeks' gestation. Study authors were contacted when required to identify additional necessary data. Data for cases that had an invasive procedure and controls were inputted into contingency tables and the risk of miscarriage was estimated for each study. Summary statistics based on a random-effects model were calculated after taking into account the weighting for each study included in the systematic review. Procedure-related risk of miscarriage was estimated as a weighted risk difference from the summary statistics for cases and controls.
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Mostacciuolo ML, Miorin M. Reapprasial of the incidence rate of Duchenne and Becker muscular dystrophies on the basis of molecular diagnosis. Neuroepidemiology ; A convenient multiplex PCR system for the detection of dystrophin gene deletions: a comparative analysis with cDNA hybridisation shows mistypings by both methods.
J Med Genet ; Mol Cells ; Rapid carrier and prenatal diagnosis of Duchenne and Becker muscular dystrophy. Nucleic Acids Res ; Abbs S. Prenatal diagnosis of Duchenne and Becker muscular dystrophy.
Prenat Diagn ; Carrier detection and prenatal molecular diagnosis in a Duchenne muscular dystrophy family without any affected relative available. Ann Genet ; Fetal gender assignment by fi rst-trimester ultrasound.
Ultrasound Obstet Gynecol ; Effi cient direct chromosomal analysis and enzyme determination from chorionic villi samples in the fi rst trimester of pregnancy. Hum Genet ; Jackson L. Prenatal genetic diagnosis by chorionic villus sampling CVS. Sem Perinatol ; J Clin Endocrinol Metab ; First-trimester biochemical and molecular diagnoses using chorionic villi: high accuracy in the U. Prenat Diagn ; Ginecol Obstet Mex ; Rapid prenatal diagnosis of aneuploidies in uncultured amniocytes by fl uorescence in situ hybridization.
Evaluation of 3, cases. Fetal Diagn Ther ; Analysis of fi ve Duchenne muscular dystrophy exons and gender determination using conventional duplex polymerase chain reaction on single cells. Mol Hum Reprod ; A simple and effective approach for detecting maternal cell contamination in molecular prenatal diagnosis. Chorionic villi sampling: laboratory experience with 4, consecutive cases.
Am J Med Genet ; Attitudes towards carrier testing in minors: a systematic review. Genet Couns ; Points to consider: ethical legal, and psychosocial implications of genetic testing in childhood and adolescents. Am J Hum Genet ; Carrier testing in minors: a systematic review of guidelines and positions statements.
Eur J Hum Genet ; Development of cardiomyopathy in female carriers of Duchenne and Becker muscular dystrophies. JAMA ;
Randomised controlled trial of genetic amniocentesis in low-risk women. Reece E. Diagnostico e Tratamento Fetal. Vol 1. Rio de Janeiro: Interlivros;
2009, Número 02
Mostacciuolo ML, Miorin M. Reapprasial of the incidence rate of Duchenne and Becker muscular dystrophies on the basis of molecular diagnosis. Neuroepidemiology ; A convenient multiplex PCR system for the detection of dystrophin gene deletions: a comparative analysis with cDNA hybridisation shows mistypings by both methods. J Med Genet ;
Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. DOI: Introduction: Early prenatal diagnosis of chromosomal abnormalities requires invasive techniques, including chorionic villous sampling CVS and amniocentesis AMC in order to acquire, culture and kayotype cells from fetuses at high risk for these abnormalities based on sonographic and biochemical markers present after week