Anti-streptolysin O ASO or ASLO is the antibody made against streptolysin O , an immunogenic, oxygen-labile streptococcal hemolytic exotoxin produced by most strains of group A and many strains of groups C and G Streptococcus bacteria. The "O" in the name stands for oxygen-labile ; the other related toxin being oxygen-stable streptolysin-S. The main function of streptolysin O is to cause hemolysis the breaking open of red blood cells — in particular, beta-hemolysis. Increased levels of ASO titre in the blood could cause damage to the heart and joints. In most cases, penicillin is used to treat patients with increased levels of aso titre. When the body is infected with streptococci, it produces antibodies against the various antigens that the streptococci produce.
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Antistreptolysin O titer profile in acute rheumatic fever diagnosis. METHODS: we investigated 78 patients with ARF at onset and follow-up, 22 with isolated chorea at onset, 45 with recurrent oropharyngeal tonsillitis, and 23 with recent flare of juvenile idiopathic arthritis. Baseline levels were observed afterwards in patients under regular penicillin prophylaxis. Keywords: arthritis, rheumatic fever, antistreptolysin, chorea. Rev Bras Reumatol Supl ; S Rev Ass Med Brasil ; Kiss MHB.
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Exame ASLO: saiba para que serve